mbe-admin | Edge Medical Communications https://madebyedge.co.uk Accurate, insightful, and engaging medical communication and education solutions to realise the promise of tomorrow’s medicines Fri, 01 Apr 2022 05:23:41 +0000 en-US hourly 1 https://wordpress.org/?v=7.1.1 https://madebyedge.co.uk/wp-content/uploads/2018/12/cropped-Edge-Medical-Communications-32x32.png mbe-admin | Edge Medical Communications https://madebyedge.co.uk 32 32 We’re recruiting https://madebyedge.co.uk/recruitment/ Thu, 15 Jul 2021 05:24:44 +0000 https://madebyedge.co.uk/?p=386

We’re recruiting

EDGE is an expanding organisation. As a result of continued growth with an established client working on an exciting blockbuster drug, we have an opportunity now to take on two professional and committed individuals to join our UK and Australian teams. This is a good opportunity for someone with a keen interest in delivering medical education programmes

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Compliance and authenticity https://madebyedge.co.uk/compliance-and-authenticity/ Fri, 06 Dec 2019 13:12:57 +0000 http://madebyedge.co.uk/?p=362

Compliance and authenticity

Back in the late 90’s, I had a lot of fun working as an interviewer with Ernie Goddard on the ‘Talking Medicine’ audiotape series. This was in the days long before podcasts, heck even before CD-ROMs.
We had long-form conversations with doctors about their therapy area and steered the conversation around to the pharmaceutical brand that we were promoting. These tapes proved very popular and Ernie had a very successful business. Listening back to some of the early interview tapes (I still have my Sony Walkman) and the questions we used to ask, and the answers that doctors gave, would never be compliant today! Boy, times have changed, both in terms of the digital technology available—you can now make a decent video with your iPhone—and in terms of compliance. It is all very locked down. Interviews are sometimes scripted and/or edited to ensure compliance. And they are short, very short. As the Edge team worked on video interviews of a group of HCPS in London yesterday, it set my head wondering about authenticity. The presentation is immaculate, the conversation perfectly compliant, and the soundbite short. But I can’t help wondering if something gets lost. How far can the conversation be pushed to give us genuine insights into their practice and stay compliant? And most doctors are storytellers. We are all storytellers. Does the story get lost? We are told that people have short attention spans, so any video must be very short. I am not so sure. Anyway, Liz and Ben from the Edge Team are off today to London to the ABPI course “Making things happen in the digital space”, to understand better compliance in the digital space. I bet there won’t be any talk of a Sony Walkman.

EDGE—communicating evidence, changing clinical practice

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Supermarkets, foreheads and PD-1 inhibitors https://madebyedge.co.uk/supermarkets-foreheads-and-pd-1-inhibitors/ Mon, 26 Aug 2019 07:17:39 +0000 http://madebyedge.co.uk/?p=305

Supermarkets, foreheads and PD-1 inhibitors

As I left the supermarket last Friday night, the squamous cell carcinoma caught my eye as I zipped down the escalator. It wasn’t a large tumour but was very prominent on the man’s forehead—an open sore on a raised wart-like lesion. Fascinating.

A classical presentation in an elderly man on a sun-exposed surface. So, what’s the story? I have recently completed a course of topical 5-fluorouracil on my own forehead to remove two actinic keratoses, the precursors of these relatively common squamous cell carcinomas. A brutal treatment, but effective. It burnt my forehead off literally, and I am now the proud owner of a new forehead. In my 50’s now, it is the closest I will get to having young, wrinkle-free skin on my face and I am running with it, and with factor 50 sunscreen to make sure it stays that way and there is no recurrence.

But what of the chap on the escalator? The vast majority are curable, but for something like 1 in 20, the spectre of metastatic disease and subsequent death is real. These skin cancers are primarily caused by cumulative, long-term exposure to ultraviolet light from the sun and are distinct from other squamous cell carcinomas, such as in the throat or genitals, that are usually linked to the human papillomavirus or smoking. The sunlight is mutagenic, and the squamous cell tumour mutation frequency is one of the highest ever seen across cancers, and higher than melanoma. And therein lies a clue to a new treatment—the high tumour mutational load identifying these tumours as potentially responsive to immunotherapy. So, it has proven to be, with some complete responses reported in clinical trials of PD-1 inhibitors and with one drug recently licensed for the treatment of locally advanced and metastatic cutaneous squamous cell carcinoma.

The avenue of immunotherapy has profoundly changed the treatment paradigm for many advanced cancers, but this is only the beginning. There is much to be done, much to be learned and much to be communicated and I am excited to be working at this edge of clinical medicine.

EDGE—communicating evidence, changing clinical practice

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Want to work at the edge of medical communications? https://madebyedge.co.uk/job-senior-medical-writer/ Mon, 26 Aug 2019 06:33:26 +0000 http://madebyedge.co.uk/?p=287

Want to work at the edge of medical communications?

We are interested in hearing from exceptional people who share our philosophy that communicating clinical evidence through high-quality medical writing and design, changes clinical practice for the better and brings commercial success for our clients. We currently have several opportunities across the business, based in our Dorking Offices.

For further details, please send your CV and/or portfolio to Liz@madebyedge.com.

EDGE—communicating evidence, changing clinical practice

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